Current Scientific Research on the Benefits of Spirulina
Contents
Detoxification
- Preclinical antitoxic properties of Spirulina (Arthrospira)
- Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study.
- The adaptive potentials of those who worked in the cleanup of the aftermath of the accident at theChernobyl Atomic Electric Power Station under the influence of different treatment methods.
- Arsenic-induced genotoxicity in Nile tilapia (Orechromis niloticus); the role of Spirulina platensis extract.
- Radioprotectant and Cytotoxic Effects of Spirulina in Relapsed Verrucous Vulvar Cancer: A Case Report.
- Radioprotective effect of extract from Spirulina platensis in mouse bone marrow cells studied by using the micronucleus test.
- The postradiation use of vitamin-containing complexes and a phycocyanin extract in a radiation lesion in rats.
- The Remedial Efficacy of Spirulina platensis versus Chromium-Induced Nephrotoxicity in Male Sprague-Dawley Rats.
- Dietary Strategies for the Treatment of Cadmium and Lead Toxicity
- Effect of spirulina and Liv-52 on cadmium induced toxicity in albino rats.
- Chemo- and radio-protective effects of polysaccharide of Spirulina platensis on hemopoietic system of mice and dogs.
- 5 Grams Daily of Spirulina REVERSED Severe Radiation Poisoning in Chernobyl Children
Anti-cancer
- Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds.
- Inhibitory effects of dietary Spirulina platensis on UVB-induced skin inflammatory responses and carcinogenesis.
- Spirulina phycocyanin induces differential protein expression and apoptosis in SKOV-3 cells.
- Radioprotectant and Cytotoxic Effects of Spirulina in Relapsed Verrucous Vulvar Cancer: A Case Report.
- Prevention of experimental oral cancer by extracts of Spirulina-Dunaliella algae.
- Tumor necrosis factor in experimental cancer regression with alphatocopherol, beta-carotene, canthaxanthin and algae extract.
- Inhibition of tumor invasion and metastasis by calcium spirulan (Ca-SP), a novel sulfated polysaccharide derived from a blue-green alga, Spirulina platensis.
- Enhancement of antitumor natural killer cell activation by orally administered Spirulina extract in mice.
- Long-term effect of Spirulina platensis extract on DMBA-induced hamster buccal pouch carcinogenesis (immunohistochemical study).
- Prevalence and parental perceptions of complementary and alternative medicine use by children with cancerin a multi-ethnic Southeast Asian population.
- Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis.
- Chemoprevention of rat liver toxicity and carcinogenesis by Spirulina.
- The effect of ultrasonificated extracts of Spirulina maxima on the anticancer activity.
- Enhancement of natural killer cell activity in healthy subjects by Immulina®, a Spirulina extract enriched for Braun-type lipoproteins.
- Cell cycle regulation and apoptotic cell death in experimental colon carcinogenesis: intervening with cyclooxygenase-2 inhibitors.
- Water soluble polysaccharides from Spirulina platensis: extraction and in vitro anti-cancer activity.
- Spirulina in health care management.
- Chemoprevention of rat mammary carcinogenesis by spirulina.
- Targeting angiogenic pathway for chemoprevention of experimental colon cancer using C-phycocyanin as cyclooxygenase-2 inhibitor.
- Chemical constituents and antiproliferative effects of cultured Mougeotia nummuloides andSpirulina major against cancerous cell lines.
- The protective effect of dietary Arthrospira (Spirulina) maxima against mutagenicity induced by benzo[alpha]pyrene in mice.
- Isolation of methyl gamma linolenate from Spirulina platensis using flash chromatography and its apoptosis inducing effect.
- Inhibitory effects of small molecular peptides from Spirulina (Arthrospira) platensis on cancer cell growth.
- In vitro antioxidant and antiproliferative activities of selenium-containing phycocyanin from selenium-enrichedSpirulina platensis.
- C-Phycocyanin inhibits cell proliferation and may induce apoptosis in human HepG2 cells.
- Alteration of mitochondrial membrane potential by Spirulina platensis C-phycocyanin induces apoptosis in the doxorubicinresistant human hepatocellular-carcinoma cell line HepG2.
- C-Phycocyanin inhibits MDR1 through reactive oxygen species and cyclooxygenase-2 mediated pathways in human hepatocellular carcinoma cell line.
- Enhancement of immune activation activities of Spirulina maxima grown in deep-sea water.
- Carvedilol and spirulina may provide important health protection to smokers and other nicotine addicts: a call for pertinent research.
- Evaluation of chemoprevention of oral cancer with Spirulina fusiformis.
- Digestion by pepsin releases biologically active chromopeptides from C-phycocyanin, a blue-colored biliprotein of microalga Spirulina.
- [Effect of polysaccharide from Spirulina platensis on hematopoietic cells proliferation, apoptosis and Bcl-2 expression in mice bearing tumor treated with chemotherapy].
- Piroxicam and c-phycocyanin prevent colon carcinogenesis by inhibition of membrane fluidity and canonical Wnt/β-catenin signaling while up-regulating ligand dependent transcription factor PPARγ.
- Estimation of serum malondialdehyde in potentially malignant disorders and post-antioxidant treated patients: A biochemical study.
- Phycocyanin induces apoptosis and enhances the effect of topotecan on prostate cell line LNCaP.
- Regulatory effects of Spirulina complex polysaccharides on growth of murine RSV-M glioma cells through Toll-like receptor 4.
- Surface decoration by Spirulina polysaccharide enhances the cellular uptake and anticancer efficacy of selenium nanoparticles.
- Chemoprevention of DMH-induced rat colon carcinoma initiation by combination administration of piroxicam and C-phycocyanin.
- Chemo- and radio-protective effects of polysaccharide of Spirulina platensis on hemopoietic system of mice and dogs.
- Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis.
- The use of complementary and alternative medicine among Malay breast cancer survivors.
- Cytotoxicity of algae extracts on normal and malignant cells.
- Modulatory potential of Spirulina fusiformis on carcinogen metabolizing enzymes in Swiss albino mice.
Anti-oxidant & Anti-inflammatory
- Anti-inflammatory and antihyperalgesic activity of C-phycocyanin.
- Hypolipidemic, antioxidant, and antiinflammatory activities of microalgae Spirulina.
- C-phycocyanin confers protection against oxalate-mediated oxidative stress and mitochondrial dysfunctions in MDCK cells.
- Anti-inflammatory activity of c-phycocyanin in lipopolysaccharide-stimulated RAW 264.7 macrophages.
- Clinical potential of phycocyanobilin for induction of T regulatory cells in the management of inflammatory disorders.
- C-phycocyanin: a biliprotein with antioxidant, anti-inflammatory and neuroprotective effects.
- Purification and identification of antioxidant peptides from enzymatic hydrolysate of Spirulina platensis.
- Role of pH on antioxidants production by Spirulina (Arthrospira) platensis.
- Quantification of Phytochemicals from Commercial Spirulina Products and Their Antioxidant Activities.
- Comparative evaluation of natural antioxidants spirulina and aloe vera for the treatment of oral submucous fibrosis.
- Antioxidant effects of Spirulina supplement against lead acetate-induced hepatic injury in rats
- Supercritical CO2 extraction of functional compounds from Spirulina and their biological activity.
- Antioxidant effects and UVB protective activity of Spirulina(Arthrospira platensis) products fermented with lactic acid bacteria.
Endurance & Performance
- Impact of Dietary Antioxidants on Sport Performance: A Review.
- Effect of Spirulina Food Supplement on Blood Morphological and Biochemical Composition in SportsmenErgogenic and antioxidant effects of spirulina supplementation in humans.
- Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress
- Spirulina promotes stem cell genesis and protects against LPS induced declines in neural stem cell proliferation.
- Efficacy of Spirulina Supplementation on Isometric Strength and Isometric Endurance of Quadriceps in Trained and Untrained Individuals – a comparative study
- Effect of Spirulina maxima on postprandial lipemia in young runners: a preliminary report.
- Effects of polysaccharide and phycocyanin from spirulina on peripheral blood and hematopoietic system of bone marrow in mice.
- Spirulina enhanced the skeletal muscle protein in growing rats.
- The effect of hydrolyzed Spirulina by malted barley on forced swimming test in ICR mice.
Anaemia
- The effects of Spirulina on anemia and immune function in senior citizens
- Management of Anemia of Inflammation in the Elderly
- Incidence of anemia and effect of nutritional supplementation on women in rural and tribal populations of eastern and northeastern India.
- Effect of Spirulina maxima Supplementation on Calcium, Magnesium, Iron, and Zinc Status in Obese Patients with Treated Hypertension.Iron availability from iron-fortified spirulina by an in vitro digestion/Caco-2 cell culture model.
- Spirulina platensis feeding inhibited the anemia- and leucopenia-induced lead and cadmium in rats
- Supplementary effect of spirulina on hematological status of rats during pregnancy and lactation.
- Update on the pharmacology of Spirulina (Arthrospira), an unconventional food.
- C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis.
- Supplementary effect of spirulina on hematological status of rats during pregnancy and lactation.
- Spirulina platensis feeding inhibited the anemia- and leucopenia-induced lead and cadmium in rats.
Cholesterol Regulation
- A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations.
- Spirulina and its hypolipidemic and antioxidant effects in humans: a systematic review.
- Antihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary report.
- The hepatoprotective and hypolipidemic effects of Spirulina (Arthrospira platensis) supplementation in a Cretan population with non-alcoholic fatty liver disease: a prospective pilot study.
- Hypolipidemic, antioxidant, and antiinflammatory activities of microalgae Spirulina.
- Effect of spirulina intervention on oxidative stress, antioxidant status, and lipid profile in chronic obstructive pulmonary disease patients.
- Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naïve patients in Yaounde-Cameroon: a randomized trial study.
- Spirulina versicolor improves insulin sensitivity and attenuates hyperglycemia-mediated oxidative stress in fructose-fed rats.
- Effects of Long-Term Supplementation of Blue-Green Algae on Lipid Metabolism in C57BL/6J mice.
- Hypolipidemic Effect of a Blue-Green Alga (Nostoc commune) Is Attributed to Its Nonlipid Fraction by Decreasing Intestinal Cholesterol Absorption in C57BL/6J Mice.
- Effects of fish oil and spirulina on oxidative stress and inflammation in hypercholesterolemic hamsters.
- Glucomannan and glucomannan plus spirulina added to pork significantly block dietarycholesterol effects on lipoproteinemia, arylesterase activity, and CYP7A1 expression in Zucker fa/fa rats.
- A randomized study to establish the effects of spirulina in type 2 diabetes mellitus patients.
Blood Pressure
- Effects of spirulina consumption on body weight, blood pressure, and endothelial function in overweight hypertensive Caucasians: a double-blind, placebo-controlled, randomized trial.
- Effects of dietary Spirulina on vascular reactivity.
- The hepatoprotective and hypolipidemic effects of Spirulina (<i>Arthrospira platensis</i>) supplementation in a Cretan population with non-alcoholic fatty liver disease: a prospective pilot study.
- Antihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary report.
- Long-Term Regulation of the Local Renin-Angiotensin System in the Myocardium of Spontaneously Hypertensive Rats by Feeding Bioactive Peptides Derived from Spirulina platensis.
- Practical prevention of cardiac remodeling and atrial fibrillation with full-spectrum antioxidant therapy and ancillary strategies.
- The hypolipidaemic effects of Spirulina (Arthrospira platensis) supplementation in a Cretan population: a prospective study.
- Phycocyanin prevents hypertension and low serum adiponectin level in a rat model of metabolic syndrome.
- One-week antihypertensive effect of Ile-Gln-Pro in spontaneously hypertensive rats.
- Effect of food diet supplements with chromium on the clinical and metabolic parameters in type 2 diabetic patients.
Anti-allergy
- Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients.
- The role of peptides derived from Spirulina maxima in down regulation of FcεRI-mediated allergic responses.
- The effects of spirulina on allergic rhinitis.
- Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients.
- Complementary ENT’: a systematic review of commonly used supplements.
- Inhibitory effect of mast cell-mediated immediate-type allergic reactions in rats by spirulina.
- Clinical potential of phycocyanobilin for induction of T regulatory cells in the management of inflammatory disorders.
- Complementary and alternative medicine for allergic rhinitis.
- Class specific influence of dietary Spirulina platensis on antibody production in mice.
- Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis.
- Calcium spirulan derived from Spirulina platensis inhibits herpes simplex virus 1 attachment to human keratinocytes and protects against herpes labialis.
Diabetes & Blood Sugar Regulation
- Antidiabetic Property of Spirulina
- Ameliorative potential of aqueous cell extract of Spirulina platensis on diabetes associated metabolic alterations
- Role of Spirulina in the Control of Glycemia and Lipidemia in Type 2 Diabetes Mellitus.
- Effect of food diet supplements with chromium on the clinical and metabolic parameters in type 2 diabetic patients
- A randomized study to establish the effects of spirulina in type 2 diabetes mellitus patients
- Effect of a zinc-enriched diet on the clinical and metabolic parameters in type 2 diabetic patients
- Spirulina versicolor improves insulin sensitivity and attenuates hyperglycemia-mediated oxidative stress in fructose-fed rats.
- Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients
- A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations
- Glucomannan and glucomannan plus spirulina-enriched squid-surimi added to high saturated diet affect glycemia, plasma and adipose leptin and adiponectin levels in growing fa/fa rats.
- Spirulina maxima prevents fatty liver formation in CD-1 male and female mice with experimental diabetes.
- Protective effects of polysacchride of Spirulina platensis and Sargassum thunbeergii on vascular of alloxan induced diabetic rats
- Exercise and spirulina control non-alcoholic hepatic steatosis and lipid profile in diabetic Wistar rats
- Study on Hypoglycaemic Effect of Spirulina platensis on Long -Evans Rats
- Attenuation of diabetic complications by C-phycoerythrin in rats: antioxidant activity of C-phycoerythrin including copper-induced lipoprotein and serum oxidation
Neuroprotective Action
- Neuroprotective effect of Spirulina fusiform and amantadine in the 6-OHDA induced Parkinsonism in rats.
- A spirulina-enhanced diet provides neuroprotection in an α-synuclein model of Parkinson‘s disease.
- Protective effects of a polysaccharide from Spirulina platensis on dopaminergic neurons in an MPTP-inducedParkinson‘s disease model in C57BL/6J mice.
- Simple in vitro assays to identify amyloid-beta aggregation blockers for Alzheimer‘s diseasetherapy.
- Neuroprotection by Spirulina platensis protean extract and phycocyanin against iron-induced toxicity in SH-SY5Y neuroblastoma cells.
- Spirulina Prevents Memory Dysfunction, Reduces Oxidative Stress Damage and Augments Antioxidant Activity in Senescence-Accelerated Mice
- Spirulina non-protein components induce BDNF gene transcription via HO-1 activity in C6 glioma cells.
- In vitro antioxidant and antiproliferative activities of selenium-containing phycocyanin from selenium-enrichedSpirulina platensis.
- Neuroprotective effect of Spirulina in cerebral ischemia-reperfusion injury in rats.
- Hypolipidemic, antioxidant, and antiinflammatory activities of microalgae Spirulina.
